An offer worth up to 100 points is worth selling again, this time in the listed occupations. Because these offers do not need an LMIA, the two ESDC lists above will not confirm most of them. The check moves to IRCC instead: an officer has to be satisfied that the employer is actively running the business, needs the role, can meet the terms of the offer, and has complied with federal and provincial employment and recruitment laws, and that you can do the job.
An offer that fails that check takes your points with it. If your application relied on an offer that was not genuine, IRCC can find you inadmissible for misrepresentation, which keeps you out of Canada for five years and bars you from applying for permanent residence in that time.